421.lcouldn't disagree more with this statement.
我坚决反对这一说法。

六级词汇讲解:

本句可用于引言段中表达作者观点。cannot disagree more with sth.意思是“完全反对”；cannot agree more with sth.意思是“完全赞同”。

句型拓展

I find such opinion flawed and hard to justify.
我认为这个观点是错误的、不合理的。

I beg to differ.
我不敢苟同。

I disagree entirely with this statement.
我完全反对这种说法。